Complete Kinase Library
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Contact us to orderComplete Kinase Library
Product ID： LM06‐KINASE
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- 产品描述
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- Commodity name: Complete Kinase Library
- Commodity ID: LM06‐KINASE
- Product Specifications: Consultation
- Sales price: Consultation
I. Product Overview
The Complete Kinase Library is a high-quality functional research resource that comprehensively covers the human kinome, encompassing 1,035 kinase‑related genes. It provides exhaustive coverage of the core kinase families involved in cellular signaling regulation, including receptor tyrosine kinases (RTKs), non‑receptor tyrosine kinases, serine/threonine kinases, lipid kinases, protein kinase regulatory factors, and other atypical kinases.
Kinases, as central regulatory components of intracellular signaling networks, modulate protein phosphorylation states and thereby participate in critical biological processes such as cell proliferation, differentiation, metabolism, immune responses, the cell cycle, DNA damage repair, and tumorigenesis and tumor progression. The Complete Kinase Library provides a comprehensive platform for systematically dissecting kinase functional networks, enabling applications including kinase‑based functional screening, drug target discovery, investigation of drug resistance mechanisms, elucidation of signaling pathways, screening of kinase inhibitors and agonists, phenotype‑driven drug discovery, and research related to precision medicine.
II. Application Scenarios
This library, integrated with high-throughput screening strategies, enables researchers to rapidly identify key kinase nodes that regulate specific cellular phenotypes, disease‑related pathways, or drug‑response mechanisms, thereby providing a systematic, highly comprehensive research tool for tumor‑targeted therapy, immune modulation, new‑drug development, and the study of complex signaling networks.
III. Core Advantages
- Precision targeting: By carefully selecting core targets within specific biological pathways, we maximize the success rate of high-throughput screening (HTS).
- Data completeness: A complete plate map and detailed files containing gene/compound information for each well (in Excel or PDF format) are provided with the shipment.
- Flexible Customization: The aliquot format can be tailored to meet specific experimental requirements, such as 96- or 384-well plates and liquid or lyophilized powder forms.
- Rigorous Quality Control: All components meet stringent industry‑standard quality criteria, such as NGS–based depth of coverage or LC/MS‑based purity verification, ensuring experimental reproducibility.
IV. Specifications and Parameters
KO Lentiviral Library CRISPRi Lentiviral Library Pool KO Lentiviral Pool KO sgRNA library 96-well / 384-well sealable microplates,
With a unique matrix barcode
1 mL cryovial 1 mL cryovial 96-well / 384-well sealable microplates,
With a unique matrix barcode
Titer per well is greater than 2E6/ml. Titer of 1E8/ml or higher Titer of 1E8/ml or higher LC-MS analysis of chemically synthesized sgRNAs shows a purity greater than 90%.
50 pmol/target (mixture of 2 sgRNAs)Store at −80°C long-term; avoid repeated freeze-thaw cycles. Utilize dry ice–based cold packs for end-to-end low-temperature cold-chain transportation. For product details and custom services, please contact Liman Bio!
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Classification: LM EasyKO Gene Knockout Kit (RNP Method)
Gene Knockout Kit Information
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